[1]陈 楠,李晓莉,张 岩.女贞子及其活性成分抗骨质疏松作用及途径研究进展[J].中国药理学通报,2018,(08):1057-1060.[doi:10.3969/j.issn.1001-1978.2018.08.006]
 CHEN Nan,LI Xiao-li,ZHANG Yan.Research progress on osteoprotective effects of Fructus Ligustri Lucidi and its active components and action pathways involved[J].Chinese Pharmacological Bulletin,2018,(08):1057-1060.[doi:10.3969/j.issn.1001-1978.2018.08.006]
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女贞子及其活性成分抗骨质疏松作用及途径研究进展()
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2018年08期
页码:
1057-1060
栏目:
讲座与综述
出版日期:
2018-08-26

文章信息/Info

Title:
Research progress on osteoprotective effects of Fructus Ligustri Lucidi and its active components and action pathways involved
文章编号:
1001-1978(2018)08-1057-04
作者:
陈 楠12李晓莉3张 岩12
1.上海中医药大学附属龙华医院脊柱病研究所,上海 200032; 2.教育部“筋骨理论与治法”重点实验室,上海 200032; 3.上海理工大学医疗器械与食品学院,上海 200093
Author(s):
CHEN Nan12 LI Xiao-li3 ZHANG Yan12
1.Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China; 2.Key Lab(Theory and Therapy of Muscles and Bones)of Ministry of Education, Shanghai 200032, China; 3.School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
关键词:
女贞子 骨质疏松 活性成分 作用途径 齐墩果酸 红景天苷
Keywords:
Fructus Ligustri Lucidi osteoporosis active components action pathway oleanolic acid salidroside
分类号:
R-05; R282.71; R284.1; R681.053.1
DOI:
10.3969/j.issn.1001-1978.2018.08.006
文献标志码:
A
摘要:
女贞子(Fructus Ligustri Lucidi)具有滋补肝肾作用。临床和科研结果显示,女贞子在治疗骨质疏松方面有广阔的应用前景。作者通过查阅国内外相关文献,综述了女贞子及其主要活性成分防治骨质疏松症的作用途径及潜在分子机制,为女贞子进一步的实验研究、药物开发和临床应用奠定科学基础。
Abstract:
It is well known that Fructus Ligustri Lucidi possesses the efficacy of tonifying liver and kidney.The clinical and scientific results have demonstrated a wide application prospects for Fructus Ligustri Lucidi in treatment of osteoporosis.After searching domestic and international relevant literatures, the authors review the action pathways and the potential molecular mechanisms involved in the effects of Fructus Ligustri Lucidi and its main active components on prevention and treatment of osteoporosis.This review provides the scientific basis for the further experimental study, drug discovery and clinical application of Fructus Ligustri Lucidi.

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备注/Memo

备注/Memo:
收稿日期:2018-04-22,修回日期:2018-05-26
基金项目:国家自然科学基金资助项目(No 81774329); 中国博士后科学基金资助项目(No 2017M610272); 上海市自然科学基金资助项目(No 17ZR1430800); 龙医创新团队(No LYCX-01)
作者简介:陈 楠(1994-),男,硕士生,研究方向:中药学; E-mail: chennanp@foxmail.com;
张 岩(1978-),男,博士,研究员,博士生导师,研究方向:药理学,通讯作者,E-mail: medicineyan@aliyun.com
更新日期/Last Update: 2018-07-26