[1]高元峰,刘昭前,李 珊,等.肿瘤中lncRNAs和circRNAs关系的研究进展[J].中国药理学通报,2018,(09):1203-1205.[doi:10.3969/j.issn.1001-1978.2018.09.005]
 GAO Yuan-feng,LIU Zhao-qian,LI Shan,et al.Study on relationship between lncRNAs and circRNAs in tumor[J].Chinese Pharmacological Bulletin,2018,(09):1203-1205.[doi:10.3969/j.issn.1001-1978.2018.09.005]
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肿瘤中lncRNAs和circRNAs关系的研究进展()
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2018年09期
页码:
1203-1205
栏目:
讲座与综述
出版日期:
2018-09-26

文章信息/Info

Title:
Study on relationship between lncRNAs and circRNAs in tumor
文章编号:
1001-1978(2018)09-1203-03
作者:
高元峰1刘昭前2李 珊1肖望重1欧阳荣1
1.湖南中医药大学第一附属医院药学部,湖南 长沙 410007; 2.中南大学湘雅医院临床药理研究所,湖南 长沙 410008
Author(s):
GAO Yuan-feng1 LIU Zhao-qian2 LI Shan1 XIAO Wang-zhong1 OUYANG Rong1
1.Dept of Pharmacy,the First Hospital of Hunan University of Chinese Medicine, Changsha 410007,China; 2.Dept of Clinical Pharmacology,Xiangya Hospital,Central South University,Changsha 410008,China
关键词:
肿瘤 长链非编码RNA 环状RNA 非编码RNA 生物靶标 药理作用
Keywords:
tumor lncRNAs circRNAs ncRNA biomarkers pharmacological effects
分类号:
R-05; R342.2; R73-3; R730.2
DOI:
10.3969/j.issn.1001-1978.2018.09.005
文献标志码:
A
摘要:
随着基因测序技术的发展,越来越多的长链非编码RNAs(lncRNAs)和环状RNAs(circRNAs)在肿瘤的研究中被发现,并引起学者对它们持续的关注。lncRNAs和circRNAs同属非编码RNA,在起源和功能上两者存在着密切关系,现均被证实在肿瘤发生、发展中发挥重要作用。该文总结了lncRNAs和circRNAs国内外的最新研究进展,专注于它们之间的关系,进一步了解与区分,以期更好识别肿瘤生物标志物。
Abstract:
With the development of whole genome and transcriptome sequencing technologies, a growing body of long noncoding RNAs(lncRNAs)and circular RNAs(circRNAs)has been identified and is receiving increasing attention. LncRNAs and circRNAs are non-protein encoding transcripts whose functions are crucial for advancing our comprehensive understanding of biological processes in human health and diseases, specifically tumor. And there is a close relationship between circRNAs and lncRNAs in their origin and function. In this paper, we have reviewed the recent advances of lncRNAs and circRNAs in tumor by focusing on their relationships, which may help to distinguish them and identify tumor biomarkers further.

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备注/Memo

备注/Memo:
收稿日期:2018-04-20,修回日期:2018-05-16
基金项目:湖南省中医药管理局临床药学重点专科(湘中医药函【2017】11号)
作者简介:高元峰(1983-),男,博士,主管药师,研究方向:肿瘤药理学、临床药理学,E-mail:davin@126.com;
欧阳荣(1964-),女,学士,教授,硕士生导师,研究方向:药学及中药学,通讯作者,E-mail:ouyangrong126@126.com
更新日期/Last Update: 2018-08-26