参考文献/References:
[1] West A B, Lockhart P J, Ofarell C, Farrer M J.Identification of a novel gene linked to parkin via a bi-directional promoter [J].J Mol Biol,2003,326(1):11-9.
[2] 邓 婕, 李怡芳, 栗原博,等.线粒体损伤与修复在帕金森病中的作用[J].中国药理学通报, 2015,31(7):906-9.
[2] Deng J, Li Y F, Hiroshi K, et al.Role of mitochondrial damage and repair in Parkinson's disease.[J].Chin Pharmacol Bull, 2015,31(7):906-9.
[3] Ikeda T.Parkin-co-regulated gene(PACRG)product interacts with tubulin and microtubules [J].FEBS Lett, 2008,582(10):1413-8.
[4] Mizuno K, Dymek E E, Smith E F.Microtubule binding protein PACRG plays a role in regulating specific ciliary dyneins during microtubule sliding [J].Cytoskeleton, 2016,73(12):703.
[5] Li W, Tang W, Teves M E, et al.A MEIG1/PACRG complex in the manchette is essential for building the sperm flagella [J].Development, 2015,142(5):921-30.
[6] Imai Y, Soda M, Murakami T, et al.A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death [J].J Biol Chem,2003,278(51):51901.
[7] Dawe H R, Farr H, Portman N, et al.The parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis [J].J Cell Sci,2005,118(Pt 23):5421.
[8] Keller L C, Romijn E P, Zamora I, Marshall W F.Proteomic analysis of isolated chlamydomonas centrioles reveals orthologs of ciliary-disease genes [J].Curr Biol,2005,15(12):1090.
[9] Lorenzetti D, Bishop C E, Justice M J.Deletion of the Parkin coregulated gene causes male sterility in the quakingviable mouse mutant [J].Proc Natl Acad Sci USA,2004,101(22):8402-7.
[10] Wilson G R, Sim M L, Brody K M, et al.Molecular analysis of the parkin co-regulated gene and association with male infertility [J].Fertil Steril, 2010,93(7):2262-8.
[11] Wilson G R, Wang H, Egan G F, et al.Deletion of the Parkin co-regulated gene causes defects in ependymal ciliary motility and hydrocephalus in the quakingviable mutant mouse [J].Humn Mol Genet, 2010,19(8):1593-602.
[12] Thumberger T, Hagenlocher C, Tisler M, et al.Ciliary and non-ciliary expression and function of PACRG during vertebrate development [J].Cilia, 2012,1(1):13.
[13] Taylor J M, Song Y J, Huang Y, et al.Parkin co-regulated gene(PACRG)is regulated by the ubiquitin-proteasomal system and is present in the pathological features of parkinsonian diseases [J].Neurobio Dis,2007,27(2):238-47.
[14] Taylor J M, Brody K M, Lockhart P J.Parkin co-regulated gene is involved in aggresome formation and autophagy in response to proteasomal impairment [J].Exp Cell Res, 2012,318(16):2059-70.
[15] Deng H, Le W D, Xie W J, et al.Genetic analysis of parkin co-regulated gene(PACRG)in patients with early-onset parkinsonism [J].Neurosci Lett, 2005,382(3):297-9.
[16] Taylor J M, Wu R M, Farrer M J, et al.Analysis of Parkin co-regulated gene in a Taiwanese-ethnic Chinese cohort with early-onset Parkinson's disease [J].Parkinsonism Relat Disord,2009,15(6):417-21.
[17] Mira M T, Alcais A, Van Thuc N, et al.Susceptibility to leprosy is associated with PARK2 and PACRG [J].Nature,2004,427(6975):636-40.
[18] Alter A, Fava V M, Huong N T, et al.Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy [J].Hum Genet, 2013,132(1):107-16.
[19] Bakija-Konsuo A, Muli C' R, Braska V, et al.Leprosy epidemics during history increased protective allele frequency of PARK2/PACRG genes in the population of the Mljet Island, Croatia [J].Eur J Med Genet, 2011,54(6):e548-52.
[20] Toma M I, Wuttig D, Kaiser S, et al.PARK2 and PACRG are commonly downregulated in clear-cell renal cell carcinoma and are associated with aggressive disease and poor clinical outcome [J].Genes Chromosomes Cancer, 2013,52(3):265-73.
[21] Agirre X, Romangomez J, Vazquez I, et al.Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia [J].Int J Cancer,2006,118(8):1945-53.
[22] Ichimura K, Mungall A J, Fiegler H, et al.Small regions of overlapping deletions on 6q26 in human astrocytic tumours identified using chromosome 6 tile path array-CGH [J].Oncogene,2006,25(8):1261-71.
[23] Udina I G, Kordicheva S, Pospelov L E, et al.Study of the polymorphic markers--the PARK2 and PACRG genes due to the incidence of pulmonary tuberculosis in two districts of the Republic of Tyva [J].Probl Tuberk Bolezn Legk,2007,(7):27-9.
[24] Ali S, Vollaard A M, Widjaja S, et al.PARK2/PACRG polymorphisms and susceptibility to typhoid and paratyphoid fever [J].Clin Exp Immunol,2006,144(3):425-31.
[25] Loucks C M, Bialas N J, Dekkers M P J, et al.PACRG, a protein linked to ciliary motility, mediates cellular signaling [J].Mol Biol Cell, 2016,27(13):2133-44.